![]() 4 Moreover, the EDX microanalysis on the pathological deposition of calcium has been useful to characterize the differences in the elemental composition of breast calcifications, in particular the composition of benign and malignant lesions 5 or the tight association of asbestos nano-fibers and lung cancer cells. where they show a metallosis following a shoulder hemi - arthroplasty with a humeral component resurfacing shoulder replacement. to study how infection associated to prosthesis could be linked to metallosis 3 or in the case report of Khan et al. 2 Otherwise, EDX was used by Barba et al. 1 In another study, authors investigated whether the impact of heavy metals accumulation in bone tissues could be related to the altered bone metabolism and architecture of osteoporotic patients. In particular, EDX microanalysis can carry a huge vantage in the detection of heavy metals pollutions as it has been demonstrated by Scimeca et al. EDX technique is also used in the study of environmental pollution. In fact, EDX technique is made particularly useful in the study of drugs delivery in which the EDX is an important tool in order to detect nanoparticles (generally, used to improve the therapeutic performance of some chemotherapeutic agents). The Energy Dispersive X-ray (EDX) microanalysis is involved in different biomedical fields of study due to its high sensitivity in detecting the different elements in tissues. ![]() ![]() In conclusion, the EDX can be considered as a useful tool in all works that require element determination, endogenous or exogenous, in the tissue, cell or any other sample. EDX is also used in the study of environmental pollution and in the characterization of mineral bioaccumulated in the tissues. EDX technique is made useful in the study of drugs, such as in the study of drugs delivery in which the EDX is an important tool to detect nanoparticles (generally, used to improve the therapeutic performance of some chemotherapeutic agents). The spectrum of EDX microanalysis contains both semi-qualitative and semi-quantitative information. Nevertheless, most of the scientific community is not fully aware of its possible applications. ![]() The EDX microanalysis is used in different biomedical fields by many researchers and clinicians. The Energy Dispersive X-ray (EDX) microanalysis is a technique of elemental analysis associated to electron microscopy based on the generation of characteristic Xrays that reveals the presence of elements present in the specimens. ![]()
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